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pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May possibly bring about lack of virologic reaction and feasible resistance.pentobarbital will decrease the level or result of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 meta